Cannabis and cannabinoids in dermatology: a systematic review and meta-analysis of quantitative outcomes.

ABSTRACT:

Objective

Cannabinoids, present in Cannabis sativa, modulate the signaling and receptor expression of the endocannabinoid system (ECS), potentially impacting various skin conditions. However, current evaluations of their clinical effectiveness remain largely descriptive. This study aimed to quantitatively assess the effectiveness of cannabinoids, including Cannabis sativa extracts, in treating dermatologic disorders.

Design

Systematic review and meta-analysis.

Data sources

PubMed, Embase, Scopus, Web of Science, and CENTRAL from inception to 30 June 2024.

Eligibility criteria for selecting studies

We included randomized controlled trials and observational studies that evaluated the efficacy or effectiveness of medical cannabis or cannabinoid-based

SUBMITTER: Sermsaksasithorn P 

PROVIDER: S-EPMC12575346 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature