Choroidal thickness as a biomarker of systemic inflammation in patients with polymyalgia rheumatica.

ABSTRACT:

Objective

Choroidal thickness (CT) varies with systemic inflammatory activity in diseases such as spondyloarthritis, suggesting its potential role as a biomarker. This study aimed to evaluate changes in CT in patients recently diagnosed with Polymyalgia Rheumatica (PMR) who are undergoing corticosteroid therapy, over a six-month follow-up period.

Methods

It is a prospective, observational, longitudinal pilot study including 20 patients with recent PMR diagnosis from two centres. All participants met PMR classification criteria. Participants underwent three visits: at diagnosis (baseline), at 3 and 6 months after starting corticosteroids. Each visit included physical examination, musculoskeletal ultrasound (MSK US) of shoulders and hips, blood tests including C-reactive prote

SUBMITTER: Trives-Folguera L 

PROVIDER: S-EPMC12575362 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature