The dilemma of chronic kidney disease and end-stage kidney disease following pre-eclampsia: a literature review and meta-analysis.

ABSTRACT:

Purpose

Pre-eclampsia (PE) is a pregnancy-related multisystem syndrome, characterized by the sudden onset of hypertension after 20 weeks' gestation. Although previous studies and meta-analyses found an association between pre-eclampsia and chronic kidney disease or end-stage kidney disease later in life, it remains unclear whether this relationship is causal. Furthermore, research conducted to date has not consistently excluded women with chronic hypertension and/or kidney disease prior to pregnancy, indicating a possible selection bias. Therefore, we undertook a systematic review of the updated literature on renal outcomes in women who were healthy prior to pregnancy and experienced pre-eclampsia.

Methods

We searched PubMed-MEDLINE and Embase for eligible studies. We includ

SUBMITTER: Bianchi G 

PROVIDER: S-EPMC12575586 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature