Low awareness of clozapine-induced agranulocytosis in a mixed-method survey of 354 patients and carers.

ABSTRACT: Current preventative measures for clozapine-induced agranulocytosis (CIA) include indefinite haematological monitoring. Another safeguard against CIA is patient and carer education to identify and respond to potential symptoms of this adverse effect. Our aim was to explore how informed patients and carers are about the potential symptoms of CIA and what actions to take. An anonymous cross-sectional survey was distributed electronically to patients or family/carers prescribed clozapine across England. A mixed methods approach was used to assess how informed patients and carers are about CIA, identifying potential symptoms of CIA and the appropriate actions to take. Quantitative data were analysed using descriptive and inferential statistics, and qualitative responses were analysed thematica

SUBMITTER: Oloyede E 

PROVIDER: S-EPMC12575722 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature