Heterologous expression of Arabidopsis FLS2 in Nicotiana benthamiana confers responsiveness to Ralstonia flg22 and activation of anti-bacterial immunity.

ABSTRACT: The association between Arabidopsis FLS2 and BAK1/SERK3 triggered by bacterial flagellin is the best-studied example of plant PRR receptor/co-receptor complex. Although most plants are able to perceive the flagellin epitope flg22 from most bacterial species, certain pathogens, such as Agrobacterium tumefaciens or Ralstonia solanacearum, have evolved polymorphisms in their flg22 sequence, avoiding perception by most plants tested so far. Specific plant species, such as Vitis riparia or Glycine max, respectively, have subsequently evolved FLS2 versions with the ability to recognize these polymorphic flg22 peptides. The model plants Arabidopsis or N. benthamiana are not able to perceive the flg22 peptide from R. solanacearum (flg22^Rso). However, in this work, we found that the expr

SUBMITTER: Li M 

PROVIDER: S-EPMC12576447 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature