Evoked slow oscillations and dynamic network reorganization after stroke.

ABSTRACT: A focal ischemic lesion is thought to alter neuronal activity beyond the area of structural damage, thereby interfering with the whole network architecture. Here, we used a combination of transcranial magnetic stimulation and electroencephalography in conjunction with dynamic connectivity analyses and graph theory to study alterations and reorganization of cortical connectivity in a cohort of 41 patients longitudinally after stroke. We found a link between an increase in low-frequency coupling in the delta band and alterations in neural information processing in the first weeks after stroke and their relevance for motor outcome >3 months later. We demonstrated that stroke enhances slow activity and delta coupling between frontocentral and parietal regions. In addition, we observed a loss o

SUBMITTER: Tscherpel C 

PROVIDER: S-EPMC12576543 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature