Decoding the <i>Penicillium italicum</i>-<i>Citrus</i> Interaction: Untargeted Metabolomics Sheds Light on a Neglected Postharvest Pathogen.

ABSTRACT: Penicillium italicum, the causal agent of citrus blue mold, is a major postharvest pathogen that reduces fruit quality and global citrus productivity. Understanding the molecular basis of infection is crucial to reveal virulence mechanisms, host defense responses, and potential targets for disease control. Here, we investigated the metabolic profile of theCitrus sinensis-P. italicum interaction using mass spectrometry-based metabolomics and desorption electrospray ionization mass spectrometry imaging. Key differentialP. italicum-derived metabolites were identified, including 12,13-dehydroprolyltryptophanyldiketopiperazine, deoxybrevianamide E, dehydrodeoxybrevianamide E, deoxyisoaustamide, and brevianamide F. To assess its biological role, brevianamide F was che

SUBMITTER: Silva E 

PROVIDER: S-EPMC12576830 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature