Study protocol to evaluate an integrated intervention using a pill ingestible sensor system to trigger actions on multifaceted social and behavioral determinants of health among PLWH: an open-label, usual care-controlled, randomized trial.

ABSTRACT:

Background

A pillar in the effort to end the HIV epidemic, the "Undetectable equals Untransmittable" (U = U) campaign has led to reduced HIV stigma and empowered people living with HIV (PLWH). Viral suppression, which eliminates risk of sexual HIV transmission, highlights the crucial role of adherence to antiretroviral therapy (ART). Strategies to enhance adherence have primarily focused on pill-taking reminders, often without real-time monitoring or interventions to address social and behavioral determinants of health (SBDOH). Suboptimal adherence to antiretroviral therapy often requires interventions from multidisciplinary teams, including nurses, social workers, and case managers to address SBDOH. These interventions often only occur weeks to months after adherence problems are

SUBMITTER: Liu H 

PROVIDER: S-EPMC12577087 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature