Genetic architecture of resistance to plant secondary metabolites in Photorhabdus entomopathogenic bacteria.

ABSTRACT:

Background

Entomopathogenic nematodes of the genus Heterorhabditis establish a symbiotic association with Photorhabdus bacteria. Together, they colonize and rapidly kill insects, making them important biological control agents against agricultural pests. Improving their biocontrol traits by engineering resistance to plant secondary metabolites (benzoxazinoids) in Photorhabdus symbiotic bacteria through experimental evolution has been shown to increase their lethality towards benzoxazinoid-defended larvae of the western corn rootworm, a serious crop pest of maize, and it is therefore a promising approach to develop more efficient biocontrol agents to manage this pest. To enhance our understanding of the genetic bases of benzoxazinoid resistance in Photorhabdus bacteria, we conducted

SUBMITTER: Boss A 

PROVIDER: S-EPMC12577137 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature