Heavy proteinuria of 25.4 g per 24 hours in a 52-year-old patient from Ethiopia with steroid-responsive minimal change disease: a case report.

ABSTRACT:

Introduction

Nephrotic syndrome refers to a distinct constellation of clinical and laboratory features of renal disease. The majority of cases of glomerular proteinuria range from 1 to 15 g of protein per 24 hours of urine. Heavy proteinuria of 25.4 g with steroid-responsive nephrotic syndrome is a rare clinical presentation of glomerulopathy. This patient presented with a significantly high degree of proteinuria in the context of retroviral infection with steroid-responsive nephrotic syndrome, which is a rare clinical scenario.

Case presentation

A 52-year-old male patient from Ethiopia with human immunodeficiency virus for the past 13 years on antiretroviral therapy with undetectable viral load presented with a 2-year history of intermittent generalized body swelling. Physi

SUBMITTER: Kassie YG 

PROVIDER: S-EPMC12577259 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature