Impact of sarcopenia on clinical outcomes of older adults undergoing total knee arthroplasty for osteoarthritis: a systematic review and meta-analysis.

ABSTRACT:

Background

Sarcopenia is increasingly recognized as a significant factor influencing postoperative outcomes in orthopedic procedures. This study aimed to systematically evaluate the impact of sarcopenia on clinical outcomes in patients undergoing total knee arthroplasty (TKA) for knee osteoarthritis (KOA), specifically focusing on knee function, quality of life, and complications.

Methods

We conducted a comprehensive search on PubMed, Embase, and CENTRAL platforms, to identify eligible studies comparing clinical outcomes of sarcopenic and non-sarcopenic patients undergoing primary TKA for KOA. Heat map was generated to intuitively illustrate the statistical differences in various clinical outcomes between sarcopenia and non-sarcopenia patients. Meta analyses were also perfor

SUBMITTER: Zhang XY 

PROVIDER: S-EPMC12577362 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature