Expression of CD73 and VEGF in salivary gland carcinomas: associations with clinicopathological characteristics in Vietnamese population.

ABSTRACT:

Background

Salivary gland carcinoma is a rare malignancy with diverse histological subtypes and poor prognosis, particularly when diagnosed at advanced stages. Recent evidence suggests that biomarkers such as CD73 and VEGF may play important roles in tumor progression and immune evasion, yet limited studies have evaluated their expression and clinical significance in Southeast Asian populations. This study aimed to determine the expression rates of CD73 and VEGF in salivary gland carcinoma and identify clinicopathological factors associated with their expression in a Vietnamese patient cohort.

Methods

A retrospective study was conducted on 111 salivary gland carcinoma patients who underwent surgical treatment in Ho Chi Minh City, Vietnam. Immunohistochemical analysis of CD73

SUBMITTER: Nguyen TD 

PROVIDER: S-EPMC12577387 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature