Mapping Postictal Aphasia through Signal Complexity: A Stereo-Electroencephalography Study.

ABSTRACT:

Objective

The postictal period provides an opportunity to investigate the pathophysiology underlying aphasia and recovery following epileptic seizures. This study examines postictal aphasia in stereo-electroencephalography (SEEG)-explored patients to identify brain regions associated with task-specific language deficits using signal complexity analysis.

Methods

We evaluated video-SEEG-recorded focal seizures with and without postictal aphasia in patients with SEEG-confirmed hemispheric language dominance. SEEG traces were analyzed using permutation entropy (PE), with the postictal period quantified by a PE-based metric, the Postictal Alteration Time (PAT). Brain region PAT was correlated with language function recovery (eg, repetition). Electro-clinical recuperation was also

SUBMITTER: Bratu IF 

PROVIDER: S-EPMC12577677 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature