Associations between epileptic seizures in pregnancy and adverse pregnancy outcomes: A systematic review and meta-analysis.

ABSTRACT:

Background

Epileptic seizures during pregnancy may increase the risk of adverse pregnancy outcomes. Socioeconomic disparities in epilepsy incidence may extend to seizure control. We conducted a systematic review and meta-analysis to assess the association between epileptic seizures during pregnancy and adverse pregnancy outcomes. We also evaluated the association between socioeconomic and individual-level factors and seizure occurrence.

Methods and findings

We searched MEDLINE, Embase, CINAHL, and PsycINFO databases from inception to May 2025 for observational studies on pregnant women with epileptic seizures. We compared maternal and foetal outcomes in pregnant women with and without seizures and assessed the association between seizure occurrence and socioeconomic or indiv

SUBMITTER: Olalere O 

PROVIDER: S-EPMC12578136 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature