Estimated glucose disposal rate and risk of metabolic syndrome: A population-based study.

ABSTRACT:

Aims

This study aims to explore the association between the estimated glucose disposal rate (eGDR) and the risk of metabolic syndrome (MetS), with a focus on the mediating role of BMI.

Methods

Data for this study came from the 2011 and 2015 China Health and Retirement Longitudinal Study. We used multivariable logistic regression and restricted cubic splines to assess the relationship between eGDR and MetS, with subgroup and interaction analyses to identify moderating factors. The diagnostic ability of eGDR for MetS was evaluated via receiver operating characteristic curves.

Results

In total, 3,229 participants were included, with 745 (23.07%) diagnosed with MetS. In the fully adjusted model, each interquartile range increase in eGDR was associated with a 58% reduced M

SUBMITTER: Zhang L 

PROVIDER: S-EPMC12578165 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature