Pan-immune inflammation value: A novel biomarker for cataract.

ABSTRACT:

Background

Inflammation significantly contributes to cataract formation; Pan-immune inflammation value (PIV) is an emerging marker that may reflect systemic inflammation. This study aimed to explore the connection between PIV and cataract formation.

Methods

We analyzed 8,235 participants from the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2008. PIV was log-transformed, and weighted logistic regression, restricted cubic splines (RCS), subgroup, and sensitivity analyses were performed to evaluate associations. The receiver operating characteristic (ROC) curves were used to assess predictive performance.

Results

Cataract prevalence was 6.6%. Higher ln-PIV was positively associated with cataract prevalence [OR=1.35, 95%CI: 1.08-1.69, P = 0.

SUBMITTER: Wang CX 

PROVIDER: S-EPMC12578218 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature