Plasma fatty acid composition predicts bone mineral accrual from childhood to adolescence: the Physical Activity and Nutrition in Children study.

ABSTRACT: Little is known about the associations of plasma fatty acids (FAs) with bone mineral accrual, and the evidence is mostly based on cross-sectional data. In this observational study, we investigated for the first time the longitudinal associations of plasma FA composition as well as desaturase and elongase enzyme activities with BMD from childhood to adolescence. Altogether, 480 children (227 girls) aged 7-9 yr attending baseline examinations were included in the current analyses. The longitudinal associations of the proportions of FAs in plasma phospholipids, analyzed by gas chromatography, as well as estimated desaturase and elongase activities with total body less head BMD, measured by dual-energy X-ray absorptiometry, were analyzed by linear mixed-effects models using values from baselin

SUBMITTER: Lakka TA 

PROVIDER: S-EPMC12578281 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature