Risk Factors and Reoperation Rate in Revision Lumbar Disc Herniation Surgery: A Systematic Review and Meta-Analysis of 1,031,348 Patients.

ABSTRACT: Study DesignA systematic review and meta-analysis.ObjectivesTo estimate reoperation rate after lumbar disc herniation surgery and identify associated risk factors.MethodsWe searched PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, Scopus, and Embase to April 2025 for English-language randomized controlled trials and observational studies reporting risk factors and reoperation rates. Two reviewers independently screened studies, extracted data, and assessed quality using the Newcastle-Ottawa Scale and Cochrane Risk of Bias 2.0 tool. Meta-analysis used fixed-effect model.ResultsTwenty-five studies (1,031,348 patients) met the inclusion criteria. The pooled reoperation rate was 8.5% (95% CI: 6.2%-11.6%), rising with follow-up: 4% at ≤1 year, 11.1% at 1-5 years

SUBMITTER: Samir A 

PROVIDER: S-EPMC12578623 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature