Helicobacter pylori and Impaired Early Childhood Development-Evidence From a Birth Cohort Study From Ghana and Cote d'Ivoire.

ABSTRACT:

Background

Helicobacter pylori (H. pylori) infection is highly prevalent in low-resource settings and has been implicated in adverse health outcomes beyond the gastrointestinal tract, including potential effects on early neurodevelopment. However, data from sub-Saharan Africa is limited.

Methods

We conducted a prospective cohort study among 229 mother-child dyads from Ghana and Côte d'Ivoire to assess the association between H. pylori infection and early child development at 12 months of age. Child development was evaluated using the Developmental Milestones Checklist (DMC), encompassing locomotor, fine motor, language, and personal-social domains. H. pylori infection status was determined by stool antigen testing. Quantile regression models, adjusted for socioeconomic statu

SUBMITTER: Eberhardt KA 

PROVIDER: S-EPMC12578653 | biostudies-literature | 2025 Sep-Oct

REPOSITORIES: biostudies-literature