Hyperglycemia in the diabetic range, but not previous diagnosis of diabetes mellitus, is an independent indicator of poor outcome in patients hospitalized for severe COVID-19.

ABSTRACT:

Aims

Diabetes mellitus (DM) and hyperglycemia are associated with poor outcome(s) in COVID-19 hospitalized patients, but their independent impact on prognosis remains unclear. We aimed to assess the impact of DM and hyperglycemia on COVID-19 outcomes.

Methods

Clinical data/records from COVID-19 patients admitted to the Parma University-Hospital (February 23rd to March 31st, 2020) were retrieved and analysed (NCT04550403). Fasting plasma glucose (FPG), inflammatory markers and the main biochemical variables were collected at admission. Patients underwent chest high-resolution CT and arterial blood gas analysis to determine the PaO₂/FiO₂ ratio (P/F ratio). The primary outcome was a composite of intensive care unit admission and/or death.

Results

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SUBMITTER: Dei Cas A 

PROVIDER: S-EPMC12578703 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature