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Clinicopathological features and prognosis of patients with colorectal Mucinous adenocarcinoma mixed with other pathological components: a nationwide retrospective study in China.


ABSTRACT:

Background

Mucinous adenocarcinoma (MAC) is typically admixed with other pathological components, including conventional adenocarcinoma, signet ring cell carcinoma, and/or neuroendocrine neoplasms. Specifically, signet ring cell differentiation (MASD) is defined as a signet ring cell component comprising less than 50% of the tumor, and neuroendocrine differentiation (MAND) is defined as a neuroendocrine component constituting less than 30%. Furthermore, MAC admixed with conventional adenocarcinoma was defined as classic mucinous adenocarcinoma (CMAC) in this study. Therefore, the study aimed to investigate the clinicopathologic and prognostic differences between patients with CMAC and those with either MASD or MAND [collectively termed mucous adenocarcinoma mixed with other patholo

SUBMITTER: Yuan J 

PROVIDER: S-EPMC12578715 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature