Maternal cardiovascular health and offspring neurodevelopment within the first five years of life: a birth cohort study.

ABSTRACT:

Background

The first five years of life are sensitive periods for neurodevelopment. Poor maternal metrics of cardiovascular health may influence offspring neurodevelopment. Previous studies focused only on one or two metrics, or different time window. This study is aimed to investigate the effects of combined cardiovascular health metric exposure during pregnancy on the neurodevelopment of offspring during crucial periods.

Methods

A total of 1007 mother‒child pairs recruited from 2013 to 2016 from the Shanghai Birth Cohort were included. Five maternal cardiovascular health metrics at 28 weeks of gestation were collected. Offspring neurodevelopment at 2-3 years and 4-5 years was evaluated with the Bayley-III and Wechsler preschool and primary scale of intelligence, fourth edi

SUBMITTER: Qiu H 

PROVIDER: S-EPMC12578739 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature