The role of amygdala reactivity in affective fluctuations across social contexts.

ABSTRACT: The amygdala plays a critical role in socio-emotional processing, serving not only as a key neural substrate for shaping emotional experiences and social behavior, but also as a trait-like individual risk factor that confers heightened vulnerability to emotional disorders, including anxiety and depression. While prior research has primarily examined the link between heightened amygdala reactivity and negative affect (NA), much less is known about its relationship with positive affect (PA), particularly across different social contexts. In this study, we focused on how these associations vary based on the level of social intimacy and distinct facets of affect (e.g., high vs. low-arousal PA). Using a combined fMRI and ecological momentary assessment (EMA) approach, we examined how individual

SUBMITTER: Chung CE 

PROVIDER: S-EPMC12578825 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature