Comparison of standard polymer formula versus short peptide formula in sepsis patients with acute gastrointestinal injury.

ABSTRACT:

Background

To investigate the selection of enteral nutrition (EN) formulas for critically ill sepsis patients with acute gastrointestinal injury (AGI) grade I-II.

Methods

We conducted a retrospective cohort study on critically ill sepsis patients with AGI grades I-II. The primary outcomes were EN caloric adequacy on day 7, calories and protein gain from EN within 3-7 days, and the incidence of gastric retention and diarrhea after EN administration. We performed a subgroup analysis based on whether patients initiated EN within 48 h.

Results

In the early EN subgroup, caloric adequacy, calories and protein gain of EN on day 7 of the short-peptide group was higher than that of the standard-polymeric group (59.1% vs. 27.3%, p = 0.001; 624[0, 936] vs. 0[-360, 480], <

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12580080 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature