Prevalence and risk factors of depression in patients with diabetes mellitus: a systematic review and meta-analysis.

ABSTRACT:

Objective

This systematic review and meta-analysis examined the prevalence of depression among individuals with diabetes and identified associated risk factors.

Methods

Five databases (PubMed, Web of Science, Cochrane, ProQuest, Embase) were searched for observational studies reporting depression prevalence and multivariable-adjusted risk factors in diabetic populations. Two reviewers independently screened and extracted data. Analyses were conducted using R software.

Results

Thirty-nine studies involving 17,486 diabetic patients were included. The pooled prevalence of depression was 35% (95% CI: 30%-41%). Risk factors included age ≤60 years, female sex, being single, unemployment, physical inactivity, anxiety, limited social support, poor medication adherence, compli

SUBMITTER: Yang K 

PROVIDER: S-EPMC12580098 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature