The use of magnesium sulfate can reduce the mortality risk of cirrhosis patients: a retrospective cohort study.

ABSTRACT:

Background

Magnesium deficiency is common in patients with cirrhosis, but there is a lack of real-world evidence to support the effect of magnesium supplementation on prognosis.

Objective

To explore whether magnesium sulfate supplementation is beneficial for patients with cirrhosis using data from the MIMIC-IV database.

Methods

Patients with cirrhosis were divided into magnesium sulfate group and non-magnesium sulfate group according to medication use during hospitalization after admission to the intensive care unit (ICU). In-hospital all-cause mortality was the primary outcome, and 180-day all-cause mortality was the secondary outcome. Propensity score matching (PSM) method, univariate and multivariate regression analysis were used to evaluate the effect of magnesium

SUBMITTER: Chen B 

PROVIDER: S-EPMC12580101 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature