Toxicological effects of sublethal microcystin-LR exposure in <i>Labeo rohita</i>: histopathological, ultrastructural, immunological, and biochemical impairments.

ABSTRACT:

Introduction

Microcystins (MCs) are alarming aquatic contaminants having extensive health implications in fish. Despite growing concern, comprehensive studies on long term effects of MCs remain unexplored in Labeo rohita (rohu). This study aims to bridge the gap by investigating the pathophysiological effects of long-term sublethal exposure to microcystin-LR (MC-LR), the most toxic congener.

Methods

Healthy rohu juveniles (mean weight 25 ± 2.1 g), sourced from institute farm were acclimatized for 2 weeks. The sublethal experimental study consisted of two treatments (control group: T0 and one-tenth 96 h-LD₅₀ dose group: T1) in three replications (10 fish per tank). The toxic effects were examined after 90 days by analysing histomorphology, ultrastruct

SUBMITTER: Mohanty S 

PROVIDER: S-EPMC12580125 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature