Intake of total and selected carotenoids and colorectal cancer risk: An Italian case-control study.

ABSTRACT:

Background

Colorectal cancer (CRC) risk is influenced by diet. Carotenoids are naturally occurring pigments primarily found in fruits and vegetables. Their potential chemopreventive properties are due to antioxidant, antimutagenic, and antiproliferative characteristics.

Objectives

We investigated dietary carotenoid intakes (α-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein+zeaxanthin, and total carotenoids) in relation to CRC risk.

Methods

We used data from a case-control study on CRC conducted in Italy, which included 1953 histologically confirmed incident cases of CRC and 4154 controls. For each subject, carotenoid intake was estimated through a reproducible and valid food frequency questionnaire, using an Italian food composition database. Odds ratios (OR)

SUBMITTER: Natale A 

PROVIDER: S-EPMC12580309 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature