Comparison of opioid-free versus weak-opioid general anesthesia on quality of postoperative recovery in soldiers undergoing arthroscopic meniscal surgery.

ABSTRACT:

Objective

To determine whether opioid-free anesthesia improves early postoperative recovery compared with weak-opioid anesthesia in soldiers undergoing meniscal surgery for training-related injuries.

Method

A total of 100 patients scheduled for elective meniscal surgery were randomized into two groups (n = 50 each): weak-opioid anesthesia group (WOA) and opioid-free anesthesia (OFA) group. Anesthesia induction consisted of alfentanil 0.2 μg/kg in the WOA group and esketamine 0.2 mg/kg in the OFA group. Intraoperatively, the OFA group received esketamine 0.2 mg/kg/h, lidocaine 1 mg/kg/h, and sevoflurane (MAC 1.0-1.4). The WOA group received remifentanil 0.1 μg/kg/h and sevoflurane (MAC 0.8-1.0). The primary endpoint was the QoR15 score at 24 h postoperatively.

Resul

SUBMITTER: Sun X 

PROVIDER: S-EPMC12580354 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature