Endoscopic endonasal resection of giant pituitary adenomas - case series from the referral pituitary center.

ABSTRACT:

Purpose

The giant pituitary adenomas (GPAs) are still a challenging surgical problem. They comprise 10-15% of operated pituitary adenomas. The advances of endoscopic techniques allow the resection of pituitary tumors previously operated by transcranial approaches. The aim of the study was to review the surgical results in a series of patients with GPAs (diameter ≥ 40 mm) operated with endoscopic endonasal approach.

Methods

The study is a retrospective analysis of a series of 176 patients (66 women and 110 men) treated from the 2007 to 2023 by the endoscopic transsphenoidal surgeries for GPAs (> 40 mm). The mean age of the patients was 57.0 years (20-81 years), and the mean follow-up period was 7.5 years (0-16 years). Forty patients had 1a grade of the Lyon's clinicopathologi

SUBMITTER: Kunicki J 

PROVIDER: S-EPMC12580440 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature