Pediatric autoimmune gastritis: An international, multicentric study.

ABSTRACT:

Objectives

Autoimmune gastritis (AIG) has been poorly described in childhood. We sought to identify the patterns of manifestations of pediatric AIG at onset and to describe its laboratory, clinical, and histopathological features.

Methods

This was a retrospective, longitudinal, multicenter, cohort study enrolling histologically proven AIG patients with an onset in the pediatric age (<18 years old). We retrieved laboratory and clinical data at the time of onset and at last follow-up when available. Differences between Helicobacter pylori-exposed versus H. pylori-naïve, and anti-parietal cell antibody (PCA)-positive versus PCA-negative patients were investigated.

Results

Overall, 51 pediatric AIG patients (median age: 13 years, interquartile range: 11-16; F:M ratio 1.7:

SUBMITTER: Lenti MV 

PROVIDER: S-EPMC12580456 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature