Relationship Between Glycemic Indices and eGFR Values Among Type 2 Diabetes Mellitus Individuals With Chronic Kidney Disease Across Various Progression Stages.

ABSTRACT:

Background

T2DM is a significant contributor to hypoglycemia, mortality, CVD, as well as a leading cause of CKD. Understanding and managing glycosylation discrepancies in T2DM patients with CKD is critical because they are important in disease causation and progression. Aim of this correlation study was to investigate the accuracy of HbA1c and fructosamine as predictors of declining renal function in the context of T2DM, by comparing and evaluating their relationships with eGFR across stages 1 to 5.

Methods

We included individuals with T2DM aged over 18 years, diagnosed per ADA guidelines, and potential CKD (stage 1-5) in T2DM patients. Outcomes involved measuring HbA1c and fructosamine levels of all participants.

Results

We recruited 424 participants from Department

SUBMITTER: Vaishali K 

PROVIDER: S-EPMC12580507 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature