Incidental prostate cancer: is prostate-specific antigen density a valid predictor? A case-control study.

ABSTRACT:

Purpose

To evaluate if prostate-specific antigen density (PSAD) predicts incidental prostate cancer (iPCa) in patients undergoing robot-assisted simple prostatectomy (RASP) for benign prostatic hyperplasia (BPH).

Methods

A total of 100 consecutive patients undergoing RASP for BPH were analyzed. Patients were stratified into low-risk and higher-risk groups based on their iPCa risk: 60 patients (PSAD ⩽ 0.1 ng/mL/cc) and 40 patients (PSAD > 0.1 ng/mL/cc), respectively. Outcomes included iPCa detection rates, preoperative imaging/biopsy utilization, and postoperative complications. A multivariable logistic regression and an univariate linear regression analysis were conducted to assess whether PSAD can predict the incidence of PCA.

Results

iPCa was detected in 8% of cases

SUBMITTER: Farzat M 

PROVIDER: S-EPMC12580511 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature