Unveiling the causes of bronchiectasis exacerbations: insights from a single-center study.

ABSTRACT:

Background

Bronchiectasis exacerbations are a significant contributor to morbidity and mortality. While environmental factors, such as viral infections, are well-established triggers for exacerbations, the role of intrinsic factors, particularly chronic bacterial infections, remains incompletely understood.

Objectives

In this context, we sought to investigate the impact of chronic bacterial infections using the COVID-19 pandemic as a natural experiment, providing a unique opportunity to assess the effects of reduced external infections.

Design

A retrospective observational cohort study was conducted involving patients with non-cystic fibrosis bronchiectasis.

Methods

Data were collected via telephone interviews and medical record reviews, comparing exacerbation

SUBMITTER: Lo Casto M 

PROVIDER: S-EPMC12580516 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature