Sugar-sweetened beverages and the risk of hyperuricemia and gout: a meta-analysis.

ABSTRACT:

Objective

This meta-analysis aimed to investigate the association between sugar-sweetened beverages (SSBs), fructose, and the risk of gout and hyperuricemia.

Methods

Following PRISMA guidelines, we systematically searched PubMed, EMBASE, and Cochrane Library for observational studies from inception to March 2025. Adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using random/fixed-effects models. Subgroup analyses explored sex. Heterogeneity (I ²) and publication bias were assessed.

Results

A total of 22 studies (235,790 participants) were included. SSB intake significantly increased the risk of hyperuricemia (OR = 1.33, 95% CI: 1.23-1.44) and gout (OR = 1.21; 95% CI 1.11-1.32). Fruit juice (FJ) showed a modest association wi

SUBMITTER: Lu Y 

PROVIDER: S-EPMC12580599 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature