Effects of dietary sodium butyrate supplementation on fat metabolism in lamb adipose and liver tissues.

ABSTRACT:

Objective

Sodium butyrate (SB) is a potentially useful feed additive; however, its effects on lipid metabolism in adipose and liver tissues of lambs are still not fully explored. This study systematically examined the effects and underlying mechanisms of dietary SB supplementation on lipid metabolism in lamb adipose and liver tissues from an adipose-blood-liver perspective.

Methods

Twelve 3-month-old male lambs (22.37±2.05 kg) were randomly divided into a control group and an SB group. We measured the adipose tissue cellular morphology and lipid metabolism-related indices in both adipose and liver tissues.

Results

The results indicated that SB significantly reduces abdominal and perirenal adipose tissue mass, as well as the average area and diameter of adipocytes (p<0

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12580741 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature