Comprehensive co-expression analysis reveals candidate regulatory genes associated with carcass and meat quality traits in Neijiang and Large White pigs.

ABSTRACT:

Objective

The Neijiang indigenous pig breed of China and the Western Large White pig breed have unique meat quality and carcass characteristics. However, the genetic factors and mechanisms influencing their distinct meat and carcass traits are still not well understood. Therefore, using weighted gene co-expression network analysis (WGCNA), this study aimed to identify key genes influencing these traits.

Methods

Transcriptome data from 17 Neijiang and 22 Large White pigs, along with their carcass weight, backfat thickness, eye muscle area, meat color, and muscle pH phenotypic data, were analyzed using WGCNA. A total of 9,249 genes were used to construct a weighted gene co-expression network.

Results

Twenty-two co-expression gene modules were identified. Genes in the to

SUBMITTER: Tecku PKM 

PROVIDER: S-EPMC12580783 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature