Polydopamine-Functionalized Magnetoliposomes as Magnetic Probes for Lectin-Glycan Interaction Analysis through Brownian Relaxation.

ABSTRACT: Polydopamine-coated magnetoliposomes (PDA-MLs) are adhesive biocomposite nanomaterials commonly employed in intracellular applications such as controlled drug delivery, theranostics, and biosensing. However, the influence of their adhesive properties on lectin-glycan interactions remains unexplored. In this study, we developed PDA-MLs as magnetic sensing labels for the rapid detection of lectin-glycan binding using alternating current (AC) magnetization measurements in liquid media. The adhesive PDA-ML surface enables facile biomolecule adsorption, facilitating their integration into biosensors. The effects of dopamine-polymerization time on the morphological and functional properties of PDA-MLs were systematically investigated. Extended polymerization resulted in a thicker PDA layer that

SUBMITTER: Ryofi AN 

PROVIDER: S-EPMC12581113 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature