Bidirectional association between symptomatic knee arthritis and circadian syndrome among middle-aged and older population: an analysis from the China health and retirement longitudinal study.

ABSTRACT:

Background

Increasing evidence has shown that there was an association between arthritis and metabolism and circadian rhythms. Circadian syndrome (CircS) can serve as an overarching indicator of circadian and metabolic disturbances. However, there are limited studies investigating the longitudinal association between the symptomatic knee arthritis and circadian syndrome (CircS).

Methods

This study used the data from two waves (2011 and 2015) of the China Health and Retirement Longitudinal Study (CHARLS). CircS was diagnosed when participants exhibited four or more of the following specified components: short sleep, depression, abdominal obesity, hyperglycemia, hypertension, and dyslipidemia. Symptomatic knee arthritis was diagnosed when both concurrent pain in knee joint and

SUBMITTER: Yang Y 

PROVIDER: S-EPMC12581250 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature