Serum parathyroid hormone and risk of sarcopenia: a meta-analysis.

ABSTRACT:

Background

Parathyroid hormone plays a key role in muscle metabolism and function, yet its precise association with sarcopenia remains controversial. This meta-analysis evaluated the relationship between serum parathyroid hormone levels and the risk of sarcopenia.

Methods

We systematically searched PubMed, Embase, and Web of Science until April 2025 for observational studies on the link between parathyroid hormone levels and sarcopenia. Using random-effects models, we derived pooled odds ratios with 95% confidence intervals and conducted subgroup analyses. Sensitivity analyses were performed to ensure robustness by excluding small or low-quality studies. Study quality was assessed with modified Newcastle-Ottawa scales, and publication bias was checked using funnel plot symme

SUBMITTER: Zhu J 

PROVIDER: S-EPMC12581253 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature