Associations of the Charlson comorbidity index with asthma and mortality (NHANES 2007-2018): a cross-sectional study.

ABSTRACT:

Background

Patients with asthma often suffer from multiple comorbid conditions, which can exacerbate disease severity and elevate the risk of mortality. This study aims to investigate the relationship between the Charlson Comorbidity Index (CCI) and asthma, as well as their combined impact on mortality.

Methods

This is an observational cross-sectional study based on the NHANES database conducted from 2007 to 2018. The study included a total of 26,002 adult participants. Logistic regression was performed to assess the relationship between the CCI and asthma. Survival analysis, including Kaplan-Meier analysis and Cox regression, was conducted to investigate the combined effect of the CCI and asthma on all-cause mortality. Subgroup analyses were performed to confirm the reliabi

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12581444 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature