Application of diffusion kurtosis imaging in differentiating T0-T1 from T2 rectal tumors.

ABSTRACT:

Background

High-spatial-resolution T2-weighted imaging (HR-T2WI) has been demonstrated to overestimate the staging of early rectal cancer, which could lead to missed opportunities for organ-preserving treatments. This study aimed to investigate the value of diffusion kurtosis imaging (DKI) in distinguishing between T0-T1 and T2 rectal tumors.

Methods

A total of 138 patients with pathologically confirmed T0-T2 rectal tumors who underwent surgery between 2018 and 2023 were included. The pathological findings on tumor staging obtained from surgical specimens were used as the reference standard. The depth of tumor invasion was assessed using HR-T2WI. Kurtosis and diffusivity from DKI and apparent diffusion coefficient (ADC) from diffusion-weighted imaging were measured for the e

SUBMITTER: Ma YR 

PROVIDER: S-EPMC12581579 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature