Long-term occupational outcomes in major depressive disorder: a 10-year follow-up study of symptom and comorbidity predictors.

ABSTRACT:

Background

No study has simultaneously investigated the associations of anxiety comorbidities, persistent depressive disorder (PDD), depression, anxiety, and somatic symptoms at baseline with the total and longest durations of paid employment (DPE) as well as the total number of reasons for occupational impairment (OI) over a 10-year period among patients with major depressive disorder (MDD). The study aimed to investigate these issues.

Methods

At baseline, 290 subjects with MDD were enrolled. MDD and anxiety comorbidities were confirmed using the Structured Clinical Interview for DSM-IV-TR. The Depression and Somatic Symptoms Scale and the Hospital Anxiety and Depression Scale were employed. At the 10-year follow-up point, 113 subjects were investigated. The total and longe

SUBMITTER: Hung CI 

PROVIDER: S-EPMC12581581 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature