Early life supplementation of Lactobacillus reuteri 21 promotes broiler intestinal proliferation and differentiation through indole-3-carboxaldehyde.

ABSTRACT: Early microbial colonization is critical for poultry gastrointestinal development. This study investigated the effects of in ovo injection of Lactobacillus reuteri strain 21 (LR21) into the amniotic cavity at embryonic day 18 on intestinal colonization, development, and growth performance in broiler chickens. As indicated by FITC labeling, LR21 effectively colonized the embryonic intestine, accumulating in the proventriculus and gizzard within 24 h and migrating to the ileum and rectum by 48 h. Meanwhile, LR21 injection significantly increased daily body weight gain and daily feed intake from days 1 to 7 (P < 0.05), while had no effect on hatchability or birth weight. It significantly reduced abdominal yolk sac weight (P < 0.05) and tended to increase small intestine weight (0.05 < P < 0.1

SUBMITTER: Xu Y 

PROVIDER: S-EPMC12581723 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature