Do Skin Prick Tests Predict Nasal Provocation Test Outcomes in Allergic Rhinitis Patients?

ABSTRACT:

Background

In diagnosing allergic rhinitis (AR), conventional skin prick tests (SPTs) often fail to reflect allergen-induced nasal symptoms. Conversely, nasal provocation tests (NPTs) provide more definitive assessments but are less accessible. Therefore, we aimed to evaluate the correlation between SPT and NPT outcomes to assess SPT's predictive reliability for NPT results.

Methods

A retrospective review was performed on 106 patients who underwent simultaneous SPT and NPT for suspected perennial AR. The SPT was assessed by measuring the mean wheal diameter of Dermatophagoides pteronyssinus (Dp). The NPT was performed by administering 100 µL of a 1000 AU/mL Dp solution into both nostrils, with responses assessed by changes in the five AR-related symptoms (total nasal symptom

SUBMITTER: Lee Y 

PROVIDER: S-EPMC12581873 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature