Rapid Deep Vat Printing Using Photoclickable Collagen-Based Bioresins.

ABSTRACT: Deep vat printing (DVP) techniques, including tomographic and filamented light (Flight) printing have transformed the tissue engineering landscape by enabling layer-free bioprinting at high resolution and speeds. Importantly, collagen is one of the most widely used materials in tissue biofabrication, but DVP using collagen-based photoresins has been under-explored. In this work, photoclickable collagen-based resins are demonstrated which are compatible with DVP, enabling prints with up to 50 µm print resolution and speeds less than 20 s per cm³. These resins contain iodixanol, which acts as a refractive index matching agent to reduce optical inhomogeneities by added cells and improves the stability of the collagen-based resins under neutralized conditions. As a potential applica

SUBMITTER: Winkelbauer M 

PROVIDER: S-EPMC12581886 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature