NOODAI: a webserver for network-oriented multi-omics data analysis and integration pipeline.

ABSTRACT:

Summary

Omics profiling has proven of great use for unbiased and comprehensive identification of key features that define biological phenotypes and underlie medical conditions. While each omics profile assists characterization of specific molecular components relevant for the studied phenotype, their joint evaluation can offer deeper insights into the overall mechanistic functioning of biological systems. Here, we introduce an approach where, starting from representative traits (e.g. differentially expressed elements) obtained for each omics profile, we construct and analyze joint interaction networks. The resulting networks rely on the existing knowledge of confident interactions among biological entities. We use these maps to identify and describe central elements, which connect

SUBMITTER: Totu T 

PROVIDER: S-EPMC12582364 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature