Incidence of antiretroviral therapy regimen modification and associated factors among People Living with HIV in Beijing, China.

ABSTRACT: Durability of the initially prescribed antiretroviral therapy (ART) regimen is critical for long-term virologic suppression among people living with human immunodeficiency virus (HIV). However, data on the incidence of regimen modification and its associated factors remain limited in China. We aim to quantify the incidence of initially prescribed ART modification and identify associated baseline factors in China. Treatment-naïve adults (≥18 years) who initiated ART with complete regimen records and have documented follow-up information in Beijing, China, from 2010 to 2020 were included. The primary outcome was initially prescribed ART regimen modification. A multivariable Cox proportional hazards model was applied to evaluate factors associated with modification risk. Of 18,911 participant

SUBMITTER: Mi Y 

PROVIDER: S-EPMC12582487 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature