Longitudinal Changes in Left Ventricular Diastolic Function in Late Life: The ARIC Study.

ABSTRACT:

Background

There is limited data regarding longitudinal changes of diastolic function in the very old, who are at the highest risk for heart failure (HF).

Objectives

This study aims to quantify intraindividual longitudinal changes of diastolic function over 6 years in late life.

Methods

The authors studied 2,524 older adult participants in the prospective community-based ARIC (Atherosclerosis Risk In Communities) study who underwent protocol-based echocardiography at study visits 5 (2011-2013) and 7 (2018-2019). The primary diastolic measures were tissue Doppler e', E/e' ratio, and left atrial volume index (LAVI).

Results

Mean age was 74 ± 4 years at visit 5 and 80 ± 4 at visit 7, 59% were women, and 24% were Black. At visit 5, mean e'_septal was 5.8

SUBMITTER: Zhao L 

PROVIDER: S-EPMC12582514 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature