Differential analysis of long noncoding RNAs in peripheral blood mononuclear cells of patients with acute ischemic stroke from Baise, China: A pilot study.

ABSTRACT: As a leading cause of death globally, stroke is a severe neurological disorder, with ischemic stroke (IS) being its most prevalent form. Given the time-sensitive nature of effective treatment, there is an urgent need for novel diagnostic and therapeutic targets. Noncoding long RNAs (lncRNAs), which regulate pathological processes, hold promise as a research area. However, their role in acute IS patients warrants further investigation. This study is designed to examine the molecular foundations of differentially expressed lncRNAs in acute IS and to assess their viability as biomarkers and therapeutic targets. We conducted an pilot study on acute IS involving a case group of 3 patients and a control group of 3 nonstroke individuals with matched clinical characteristics. High-throughput lncRN

SUBMITTER: Chen B 

PROVIDER: S-EPMC12582679 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature